Triptorelin acetate cas : 57773-63-4
Unit Size |
100 mcg/vial, 2 mg, 5mg, 10 mg |
Unit Quantity |
1 Vial |
CAS NO. |
57773-63-4 |
Synonyms |
Triptorelin Acetate, GnRH |
Molecular Formula |
C64H82N18O13 |
Molecular Weight |
1311.45 |
Sequence |
pGlu-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH2 |
Appearance |
White Powder |
Purity |
98.86% |
Identity (ESI-MS) |
1311.45±1.0 |
Source |
Chemical Synthesis |
Storage |
Lyophilized powder is stable at room temperature for 90 days,however it should be stored in a freezer below -8C for any extended period of time. After reconstituting it should be refrigerated at temperatures not to exceed 36 F. |
Reports |
MS Report 1 MS Report 2 |
Terms |
The products we offer are intended for laboratory research use only. Please familiarize yourself with our Terms of Service prior to ordering. |
Triptorelin (GnRH)
Triptorelin, a decapeptide (pGlu-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH2), is a gonadotropin-releasing hormone agonist (GnRH agonist) used as the acetate or pamoate salts. Triptorelin raises testosterone levels by causing constant stimulation of the pituitary, it decreases pituitary secretion of gonadotropins luteinizing hormone (LH) and follicle stimulating hormone (FSH). Like other GnRH agonists, triptorelin may be used in the treatment of hormone-responsive cancers such as prostate cancer or breast cancer, precocious puberty, estrogen-dependent conditions (such as endometriosis or uterine fibroids), and in assisted reproduction. Triptorelin is marketed under the brand names Decapeptyl (Ipsen) and Diphereline and Gonapeptyl (Ferring Pharmaceuticals). In the United States, it is sold by Watson as Trelstar.In Middle East Triptorelin is marketed under the brand name Variopeptyl (Varian Darou Pajooh). In India, Dr. Reddy’s Laboratories has launched recently Triptorelin under the brand name “Pamorelin LA”. During the treatment of prostate cancer it does cause a surge of testosterone (an initial uplevel of testosterone levels), known as a flare effect. In men a reduction of serum testosterone levels into the range normally seen after surgical castration occurs approximately two to four weeks after initiation of therapy. Systematic IUPAC Name: [d-Trp6]GnRH [edit]References Lahlou N, Carel JC, Chaussain JL, Roger M (July 2000). “Pharmacokinetics and pharmacodynamics of GnRH agonists: clinical implications in pediatrics”. J Pediatr Endocrinol Metab .
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