BPC157 10 mg -10vial -GHRP6 10mg 10vial
BPC 157 10 mg
Molecular formula: C62H98N16O22
Molar Mass:1419.53552 g/mol
BPC 157 (Body Protection Compound-157) is a pentadecapeptide made up of 15 amino acids. The amino acids sequence in BPC 157 is similar to a portion of the human BPC amino acid sequence. Human BPC is found in the gastric juice. Experiments have shown that BPC 157 enhances the healing of wounds, including tendons wounds such as transected Achilles tendons of rats. The aim of this study was to investigate the probable mechanism that BPC 157 utilizes to accelerate the healing process in an injured tendon. The study used two group of tendon explants of which one group was cultured in a BPC 157-containing medium while the other group was cultured in a medium lacking BPC 157. These cultures were thereafter examined for tendon fibroblasts outgrowths. Such outgrowths indicated tendon regeneration.The results revealed that the explants’ outgrowth was significantly accelerated in the culture containing BPC 157 as compared to the culture lacking BPC 157. Also, a MTT assay did show that BPC 157 does not directly affect cellular proliferation in a culture of rat-derived Achilles tendon. However, results also showed that BPC 157 significantly increased the survival of cells under oxidative stress. Furthermore, the Transwell filter migration assay showed that BPC 157 significantly increased in-vitro fibroblast migration in a dose-dependent fashion. Moreover, BPC 157 accelerated the dispersal of the fibroblasts in culture dishes in a dose-dependent manner.
Additionally, FITC-phalloidin staining was able to demonstrate that BPC 157 induces F-actin formation in fibroblasts. Likewise, Western blot analysis was able to detect the production and activation of paxillin and FAK proteins. The western blot analysis also showed that BPC 157 increases the extent of phosphorylation of paxillin and FAK proteins without affecting the amounts produced.
Thus, it can be concluded that BPC 157 enhances the ex-vivo growth and in-vitro cellular migration of fibroblasts derived from rat tendon explants. Moreover, BPC 157 also increases the probability of a cell surviving under oxidative stress. These actions of BPC 157 are probably mediated by the activation (through phosphorylation) of the proteinic FAK-paxillin pathway.
GHRP 6 10mg
Important Notification: All of our products and services listed in this website are for research or production use only, not for direct human use.
The hexipeptide GHRP – 6 is a secretagogue peptide that has a molecular formula of C46H56N12O6and a molecular weight of 873.014. Its structure is comprised of six amino acids. The name of the peptide itself is an acronym that stands for Growth Hormone Releasing Peptide.
GHRP – 6 and the Pituitary Gland
Scientific study that has been based on animal test subjects has determined that the way in which GHRP 6 has been shown to function chiefly ties into its relationship with the pituitary gland; the tiny, pea-sized gland that is located at the bottom of the hypothalamus at the base of the brain. In essence, this gland is charged with the regulation and control of a host of different processes that are tied to the endocrine system. Some of these processes include metabolism, thyroid gland functionality, temperature regulation, internal water regulation, pain relief, and growth. GHRP – 6’s overall functionality is such that it inhibits the pituitary gland from blocking the production of secretions that directly tie to these regulatory processes. This then allows for the animal test subject to have the ability experience a more efficient means of achieving a level of homeostasis in regards to these regulatory processes.
GHRP – 6 and the Stomach
It has also been determined by scientific study based on animal test subjects that GHRP – 6’s overall functionality can be linked to the production of ghrelin. In essence, ghrelin is an amino acid that is primarily produced by the cells that line the stomach, although it has been noted that it can also be secreted by the epsilon cells that are found in the pancreas. The expression of this particular secretion serves to stimulate the sensation of hunger; this allows it to act as a counterbalance to amino acid leptin, whose secretion stimulates the sensation of feeling full. Studies have indicated that GHRP – 6’s functionality allows for a greater level of ghrelin to be produced. This extra level of production prolongs the amount of which an animal test subject can experience hunger. This in turn enables the test subject to intake a greater amount of food which can then be used as fuel for the pituitary gland’s elevated ability to secrete endocrine system-related expressions.
GHRP – 6 and the Liver
Further scientific study that has been based on animal test subjects has determined that GHRP – 6’s abilities have a connection with the liver; specifically, with a liver-based secretion known as Insulin-like Growth Factor-1, or IGF-1. This secretion has been shown to be highly reactive in nature, meaning that its expression has been tied to the growth and repair of muscle and tissue growth. Studies have indicated that GHRP – 6 has the capacity to influence an elevated production amount of this particular secretion, thus allowing an animal test subject a more efficient rate in achieving homeostasis on a muscular and skeletal tissue level.
GHRP – 6 and the Central Nervous System
It has also been determined through scientific study based on animal test subjects that the presence of GHRP – 6 aids in the activation of intracellular signaling pathways along the central nervous system; these pathways are ones that are used by various secretions that are tied to the pituitary gland. Additionally, it has been shown that it has the ability to promote a greater level of protein expression in terms of overall cellular survival. These functions have led to the determination that it could be a prime ally in the guarding against cell loss and functionality in the aftermath of a hypoxic-ischemic brain injury, such as:
- Angina Pectoris caused by cardiac arrest
- Angina Pectoris caused by respiratory arrest
Various Elevated Processes
Because of the way in which GHRP 6 has been shown to function, scientific study that has been based on animal test subjects has been able to determine that its presence can be responsible for several elevated processes. These processes have been thought to include an increase in muscle growth, a decrease in body fat, an elevation in muscle and tissue repair, an expedited rate of recovery from injury, a boost in bone density, increased immune system efficiency, and a boost in connective tissue and joint strengthening.
Strictly for Controlled Environments
It should be noted that any findings or observations that relate to GHRP – 6 and its overall functionality should exclusively be done within a strictly controlled environment, such as a medical research facility or a laboratory. The reason for this is due to the fact that the peptide and the study its operational is currently just fit for scientific study on animal test subjects. As such, it should be noted that research that has been derived regarding GHRP – 6 is due to scientific tests conducted in a controlled environment only.
- On time delivery
- Free sample
- 24/7/360 after sales services for all of our products
- Exporting to South America (Brazil, …) , Australia, Middle East , Europe (Austria, Germany, Italy,…), USA, Asia (Vietnam, India, Thailand,…), Africa
- The highest peptide purity more than 98%
- HPLC and MS records for any orders
- Research and development our products in Austria through our experianced team
- More than 2 decades experiances
- Accept different currancies , Such as USD, EUR, AUD, CAD, JPY, TWD, AED , HKD, CNY (RMB), …
- OEM can be accepted